Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep334 | Clinical case reports - Thyroid/Others | ECE2016

Erdheim-Chester disease and papillary thyroid carcinoma: case report of a common association in a rare disease

Aparicio David , Martins Nuno , Leichsenring Carlos , Rodrigues Alice , Joao Ana , Soares Antonio , Fragoso Marta , Marinho Rui , Rocha Ricardo , Sousa Marta , Gouminski Serguei , Sobrinho Cisaltina , Dias Wima , Afonso Enio , Geraldes Vasco , Nunes Vitor

Introdution: Erdheim-Chester disease is a rare multisystemic form of Non-langerhans cell histiocytosis CD67 positive, with approximately 550 published cases. Papillary carcinoma is the most common thyroid cancer with BRAF V600E the most common mutation. Both diseases may be associated to BRAF V600E mutation. If Erdheim- Chester disease is positive to this mutation on histiocytes, a specific pharmacolgical treatment is available, (vemurafenib), with better results.<p class=...